The Office of Portfolio Analysis and Strategic Initiatives (OPASI) provides the National Institutes of Health (NIH) and its constituent Institutes and Centers (ICs) with the methods and information necessary to manage their large and complex scientific portfolios, identifies – in concert with multiple other inputs – important areas of emerging scientific opportunities or rising public health challenges, and assists in the acceleration of investments in these areas, focusing on those involving multiple ICs.

The NIH Roadmap is intended to be an “incubator space” for programs that, due to their cross-cutting relevance and/or complexity, warrant concerted attention from NIH as a whole. Consistent with its “incubator” function, the Roadmap stimulates research or the development of research resources with the expectation that the programs will either be completed within a 5–10 year timeframe or will transition out of the “incubator space” as they become integral to IC activities.

The Council of Councils will be made up of approximately 30 members (one from each IC Advisory Council, representatives nominated by the OD program offices, and broad lay representation, including a member of the NIH Council of Public Representatives).

The NIH Steering Committee (SC) was established by the NIH Director as an efficient and transparent forum for trans-NIH governance and streamlined decision-making at NIH.

Questions and answers about purpose, impact, review, implementation, budget and financing, leadership, and governance.